Until 1632 the island?known only as l?isola inferiore or isola di sotto[1]?was a rocky crag occupied by a tiny fishing village: but that year Carlo III of the influential House of Borromeo began the construction of a palazzo dedicated to his wife, Isabella D'Adda, from whom the island takes its name. He entrusted the works to the Milanese Angelo Crivelli, who was also to be responsible for the planning the gardens. The works were interrupted around middle of the century when the Duchy of Milan was struck by a devastating outbreak of the plague.
